Endocrine Abstracts

Case: A 66-year-old female was referred to the Endocrinology clinic for suspected osteoporosis after a right femoral shaft fracture. As the site was atypical and the injury was low energy, a pathological fracture was suspected. There was a history of recurrent fractures sustained after the age of 30 years and were either spontaneous or from low-energy impacts (Table 1). Growing up, she was told that “there was something wrong with her bones” and required regular phys...

Case: A 59-year-old female with a past medical history of surgically treated primary hyperparathyroidism (PHPT) and breast cancer presented with irregular periods, post-menstrual bleeding, hot flushes, fatigue, and left loin pain. Furthermore, she reported weight gain of approximately 8 lb over 6 months and easy bruising in the absence of antiplatelet and anticoagulant therapy. There were no central, respiratory, or gastrointestinal symptoms. She was normotensive, and the clin...

Context: Respiratory failure as a component of severe hypothyroidism has high mortality and a number of pathological mechanisms have been proposed. These range from cerebral causes to neuromuscualr and pulmonary factors. Changes due to mucopolysacharide deposition in the lungs is another postulated mechanism, but radiological changes are hitherto not clinically demonstrated.Objective: A case of hypothyroidism with hypoxia associated with CT features sugg...